Cobimetinib (Cotellic) is an important kinase inhibitor primarily used for the treatment of certain types of melanoma and thyroid-like tumors. As a prescription medication, its purchase and use are subject to strict regulatory requirements.

How to Purchase Cobimetinib (Cotellic)

Overseas Purchase

Patients may choose to consult and purchase cobimetinib at hospital pharmacies or licensed drugstores in countries or regions where the medication has been launched.

Since drug prices may be affected by factors such as regional differences and exchange rate fluctuations, patients need to make a budget and plan in advance before purchasing.

Purchase via Medical Service Institutions

Patients may consult domestic overseas medical service institutions that cooperate with international pharmacies or pharmaceutical companies.

These institutions typically provide legal import channels and offer professional consultation and guidance.

Precautions for Purchasing Cobimetinib (Cotellic)

Dosage Confirmation

The recommended dosage is 60 mg taken orally once daily, administered for the first 21 days of each 28-day cycle, until disease progression or unacceptable toxicity occurs.

Physicians will develop an individualized administration plan based on the patient’s specific condition.

Medication Administration Guidance

Cobimetinib can be taken with food or on an empty stomach.

If a dose is missed or vomiting occurs after taking the medication, the regular dose should be taken at the next scheduled time.

Awareness of Adverse Reactions

Before purchasing, patients should fully understand the potential adverse reactions of the medication.

Common adverse reactions include diarrhea, photosensitivity reaction, nausea, fever, and vomiting.

If severe skin rash, bleeding, cardiomyopathy, or other symptoms occur, patients should promptly communicate with their physician and adjust the dosage as directed by the physician.

Considerations for Special Populations

Women of childbearing age need to be aware of the potential risks of the medication to the fetus and use effective contraceptive measures during treatment and for two weeks after discontinuing the medication.

Lactating women should not breastfeed during treatment and for two weeks after discontinuing the medication.

Methods to Identify Genuine Cobimetinib (Cotellic)

Packaging Identification

The packaging bottle of genuine cobimetinib should contain complete product information, batch number, expiration date, and other details.

Tablet Characteristic Inspection

Each genuine cobimetinib tablet should be a white, round, film-coated tablet with the clear embossing "COB" on one side.

During purchase, patients should carefully check whether these physical characteristics are complete.

Verification of Supplier Qualifications

Ensure that the supplier holds a legal drug distribution license and relevant qualifications.

Verify the authenticity of the supplier’s qualifications through official channels or regulatory authorities.