Odevixibat (Bylvay) is an ileal bile acid transporter (IBAT) inhibitor primarily indicated for the treatment of pruritus associated with progressive familial intrahepatic cholestasis (PFIC) and Alagille syndrome (ALGS). It is a prescription medication and must be used strictly in accordance with medical advice.

How to Purchase Odevixibat (Bylvay)

Overseas Purchase

Patients may choose to consult and purchase Odevixibat at hospital pharmacies or legitimate drugstores in countries or regions where the medication has been launched.

Since drug prices may be affected by factors such as regional differences and exchange rate fluctuations, patients need to make a budget and plan in advance before purchasing.

Purchase Through Medical Service Institutions

Patients may consult domestic overseas medical service institutions that cooperate with international pharmacies or pharmaceutical companies.

These institutions can usually provide legal import channels and offer professional consultation and guidance.

Precautions for Purchasing Odevixibat (Bylvay)

Strictly Follow Medication Guidelines

PFIC patients (3 months of age and older): The starting dose is 40 mcg/kg per day, with a maximum dose not exceeding 120 mcg/kg per day.

ALGS patients (12 months of age and older): A fixed dose of 120 mcg/kg per day is recommended.

Administration method: The medication should be taken with breakfast in the morning. Capsules must not be chewed or crushed. For pediatric patients, oral granules can be mixed with soft food or liquids for administration.

Contraindications and High-Risk Populations

Contraindications: Contraindicated in patients with decompensated liver function (e.g., hepatic encephalopathy, ascites, variceal bleeding).

Monitoring requirements: Liver function (ALT, AST, bilirubin, etc.) must be tested regularly before starting medication and during treatment, with close monitoring especially in the first 6-8 months.

Drug Interactions

Concurrent use with bile acid sequestrants (e.g., cholestyramine) should be avoided; an interval of at least 4 hours is required between their administrations.

How to Identify Genuine vs. Counterfeit Odevixibat (Bylvay)

Specification Identification

Oral granules:

200 mcg: Ivory-colored capsules imprinted with "A200"

600 mcg: Ivory-colored capsules imprinted with "A600"

Capsules:

400 mcg: Orange-and-white capsules imprinted with "A400"

1200 mcg: Orange-colored capsules imprinted with "A1200"

Check Medication Characteristics

Appearance: Tablets/capsules should be free from damage, discoloration, or abnormal odor. For example, 400 mcg capsules are bi-colored (orange and white), while 1200 mcg capsules are fully orange.

Package Insert: Genuine products are accompanied by a complete prescription information leaflet, which includes indications, administration methods, and warning contents.