Emtricitabine and Tenofovir Alafenamide Tablets (Descovy) is a fixed-dose combination preparation used for HIV-1 treatment and pre-exposure prophylaxis (PrEP). The standardized access to this medication and the safety of its use are of great importance.

How to Purchase Emtricitabine and Tenofovir Alafenamide Tablets (Descovy)

Overseas Purchase

Patients may choose to consult and purchase the medication at hospital pharmacies or legitimate retail pharmacies in countries or regions where Emtricitabine and Tenofovir Alafenamide Tablets have been launched.

Since the drug price may be affected by factors such as regional differences and exchange rate fluctuations, patients need to make a budget and plan in advance before purchasing.

Purchase through Medical Service Institutions

Patients may consult domestic overseas medical service institutions that cooperate with international pharmacies or pharmaceutical companies.

These institutions can usually provide legal import channels and offer professional consultation and guidance.

Precautions for Purchasing Emtricitabine and Tenofovir Alafenamide Tablets (Descovy)

Pre-Purchase Screening Requirements

Hepatitis B Virus (HBV) Screening: All users must undergo HBV testing before taking the medication.

Renal Function Monitoring: It is necessary to assess serum creatinine, estimated creatinine clearance rate, urine glucose, and urine protein.

HIV-1 Testing (for PrEP Population): HIV-1 testing must be conducted before starting the medication and every 3 months during the medication period.

Contraindications for Special Populations

Contraindication for HIV-1 PrEP: Use is strictly prohibited in individuals with unknown or positive HIV-1 status.

Patients with Renal Impairment: Use is not recommended for patients with a creatinine clearance rate of 15 to < 30 mL/min.

Drug Interaction Warnings

Avoid Concurrent Use with: P-glycoprotein (P-gp) inducers, such as rifampicin, carbamazepine, and St. John's Wort extract.

Protease Inhibitors: Concurrent use with tipranavir/ritonavir may lead to a decrease in the blood concentration of tenofovir alafenamide (TAF).

Authentication of Emtricitabine and Tenofovir Alafenamide Tablets (Descovy) (Genuine vs. Counterfeit)

Identification by Appearance Characteristics

200mg/25mg Tablets: Blue rectangular film-coated tablets, engraved with "GSI" on one side and "225" on the other side.

Verification of Packaging Information

Genuine products use child-resistant packaging.

The label must include key information such as the drug name, specification, batch number, and expiration date.

Verification of Pharmacological Properties

Emtricitabine is a cytidine analog that exerts its effect by inhibiting the activity of HIV-1 reverse transcriptase.

Tenofovir alafenamide (TAF) needs to be converted into tenofovir in cells, which is then phosphorylated into its active metabolite.

Verification of Official Information

Check the drug approval information on the official website of the U.S. Food and Drug Administration (FDA).

Verify the qualification of the manufacturer, Gilead Sciences, Inc.