Mavacamten (Camzyos) is the world’s first approved cardiac myosin inhibitor for the treatment of symptomatic obstructive hypertrophic cardiomyopathy (oHCM), and its standardized use is directly related to therapeutic efficacy and safety.

What Are the Purchase Channels for Mavacamten (Camzyos)?

Overseas Purchase

Patients can choose to consult and purchase the drug at hospital pharmacies or licensed pharmacies in countries/regions where mavacamten has been approved for marketing.

Since drug prices may be affected by factors such as regional differences and exchange rate fluctuations, patients need to make budget plans in advance before purchase.

Purchase via Medical Service Institutions

Patients can consult domestic overseas medical service institutions that cooperate with international pharmacies or pharmaceutical companies.

These institutions can usually provide legal import channels, as well as professional consultation and guidance services.

Precautions for Mavacamten (Camzyos) Administration

Cardiac Function Monitoring Requirements

The left ventricular ejection fraction (LVEF) must be ≥ 55% before the initiation of treatment.

Treatment must be immediately discontinued if LVEF drops below 50% during the course of therapy.

Continuous monitoring of the Valsalva left ventricular outflow tract gradient is required.

Contraindicated Drug Screening

Potent CYP2C19 inhibitors.

Moderate to potent CYP2C19 inducers.

Moderate to potent CYP3A4 inducers.

Identification of Authentic and Counterfeit Mavacamten (Camzyos)

Verification of Drug Packaging and Appearance

Authentic mavacamten is formulated as hard capsules, available in four strengths: 2.5 mg, 5 mg, 10 mg, and 15 mg.

The capsule body is opaque white, printed with the word “Mava”.

The capsule cap is opaque, printed with the dosage strength. The cap color varies by strength: purple for 2.5 mg, yellow for 5 mg, pink for 10 mg, and gray for 15 mg.

Carefully check whether the drug name, dosage, manufacturer information (Bristol-Myers Squibb), batch number, and expiration date printed on the packaging are clear and complete.

Vigilance should be exercised against any products with shoddy packaging, blurred printing, color deviations, or incomplete information.

Identification of Quality Abnormalities

The drug should be stored at a temperature between 20°C and 25°C.

If capsule breakage, abnormal discoloration, or packaging damage is found, the use of the drug should be suspended immediately.