Ziihera (zanidatamab-hrii) is a bispecific HER2-directed antibody indicated for the treatment of previously treated, unresectable or metastatic HER2-positive (IHC 3+) biliary tract cancer. Following its U.S. approval in 2024, many patients and their families have begun to focus on how to legally access this medication.

How to Purchase Ziihera (Zanidatamab-hrii)

Overseas Purchase

Patients may consult and purchase Ziihera at hospital pharmacies or licensed drugstores in countries/regions where the medication is approved for marketing.

Due to potential price variations caused by regional differences, exchange rate fluctuations, and other factors, patients should make a budget and plan in advance before purchasing.

Purchase Through Medical Service Institutions

Patients may consult domestic overseas medical service institutions collaborating with international pharmacies or pharmaceutical companies.

These institutions typically provide legal import channels and offer professional consultation and guidance.

Precautions for Purchasing Ziihera (Zanidatamab-hrii)

Strictly Follow Medical Advice

Ziihera is an intravenous medication that must be reconstituted and administered by healthcare professionals in hospitals or specialized medical institutions.

Patients must not purchase and use the medication at home independently, as this may lead to severe adverse reactions.

Confirm Medication Transportation and Storage Conditions

This medication is supplied as a lyophilized powder and must be stored refrigerated at 2°C–8°C.

At the time of purchase, patients should confirm that the medication was maintained in a cold chain throughout transportation; otherwise, efficacy may be affected or safety risks may arise.

Understand Pre-Administration Prophylaxis and Monitoring Requirements

Before Ziihera administration, premedication with acetaminophen, antihistamines, and corticosteroids is required to prevent infusion reactions.

During treatment, regular monitoring of cardiac function, liver function, and other indicators is necessary.

How to Verify the Authenticity of Ziihera (Zanidatamab-hrii)

Verify Medication Packaging Information

Authentic Ziihera is supplied as a 300 mg/vial lyophilized powder.

Brand name: ZIIHERA®.

Generic name: zanidatamab-hrii.

Manufacturer: Jazz Pharmaceuticals Ireland Limited.

Approval number (e.g., U.S. NDC code: 68727-950-01).

Batch number, manufacturing date, and expiration date.

Observe Medication Appearance

After reconstitution, the solution should be colorless to pale yellow, clear or slightly opalescent, with no visible particles.

If discoloration, turbidity, or foreign matter is observed, discontinue use immediately.

Scan Anti-Counterfeiting Labels or Query Traceability

Medication packaging in some countries/regions is affixed with anti-counterfeiting QR codes or barcodes. Patients can scan these through official channels to verify authenticity.

If the medication source is questionable, contact the manufacturer Jazz Pharmaceuticals or its authorized agents for verification.