Factors Affecting the Price of lapatinib

Absorption of oral lapatinib is incomplete and variable. The median lag time for the appearance of serum concentrations is 0.25 hours (range: 0 to 1.5 hours). The peak plasma concentration (Cmax) of lapatinib is reached approximately 4 hours after administration. Steady-state concentrations of lapatinib are achieved within 6 to 7 days of daily dosing, indicating an effective half-life of 24 hours.