Mitiglinide Calcium Tablets (Glufast) are an oral hypoglycemic drug used for the treatment of type 2 diabetes, belonging to the class of fast-acting insulin secretagogues. Its mechanism of action is to promote insulin secretion from pancreatic β-cells, thereby rapidly controlling blood glucose levels after meals.
What Are the Indications of Mitiglinide Calcium Tablets (Glufast)?
Main Indications
Mitiglinide Calcium Tablets are indicated for the treatment of type 2 diabetes.
This drug is mainly used in patients whose blood glucose remains poorly controlled despite diet management and exercise therapy.
It is characterized by rapid onset and short duration of action, making it particularly suitable for controlling postprandial blood glucose elevation.
Precautions
Patients should use this drug under the guidance of a doctor and strictly follow the prescribed dosage.
This drug is suitable for patients with a fasting blood glucose level ≥ 126 mg/dL, or a 1-hour or 2-hour postprandial blood glucose level ≥ 200 mg/dL.
Blood glucose should be monitored regularly during treatment. If the therapeutic effect is unsatisfactory after 2 to 3 consecutive months of use, consideration should be given to adjusting the treatment plan.
Specifications and Properties of Mitiglinide Calcium Tablets (Glufast)
Regular Tablets (5 mg and 10 mg)
5 mg tablets: White uncoated tablets, approximately 6.0 mm in diameter, 2.0 mm in thickness, and about 75 mg in weight.
10 mg tablets: White uncoated tablets with a score line, approximately 10.0 mm in major diameter, 5.0 mm in minor diameter, 3.0 mm in thickness, and about 150 mg in weight.
The active ingredient is mitiglinide calcium hydrate. Excipients include corn starch, hydroxypropyl cellulose, calcium stearate, microcrystalline cellulose, lactose hydrate, etc.
Orally Disintegrating Tablets (OD Tablets, 5 mg and 10 mg)
5 mg OD tablets: Pale yellowish-white uncoated tablets, approximately 6.4 mm in diameter, 3.1 mm in thickness, and about 100 mg in weight.
10 mg OD tablets: Pale yellowish-white uncoated tablets with a score line, approximately 8.0 mm in diameter, 3.8 mm in thickness, and about 200 mg in weight.
The active ingredient is also mitiglinide calcium hydrate. Excipients include D-mannitol, crospovidone, stevioside, flavoring agents, etc., which enable the tablets to disintegrate rapidly in the mouth.
Usage Characteristics
Regular tablets should be swallowed with water.
OD tablets can disintegrate rapidly in the mouth with saliva, no water is needed for swallowing, and they can also be taken with water. They are suitable for patients with swallowing difficulties. However, it should be noted that OD tablets should not be taken without water when lying in bed.
Storage Methods for Mitiglinide Calcium Tablets (Glufast)
Storage Environment
All specifications of tablets should be stored at room temperature, away from high temperatures, moisture, and direct sunlight.
Expiration Period
The expiration period of regular tablets (5 mg and 10 mg) is 3 years.
The expiration period of orally disintegrating tablets (OD tablets) is 5 years.
Precautions
The drug should be stored out of the reach of children.
Drugs in PTP (Press-Through Package) blister packs must be taken out of the aluminum foil before use to avoid accidental ingestion of the package, which may cause esophageal injury.
After opening the package of OD tablets, moisture should be avoided. It is recommended to store them in a sealed container to prevent the tablet surface from absorbing moisture and affecting quality.
