Perfluorohexyl Octane Eye Drops (Miebo) is a new ophthalmic therapeutic drug approved by the U.S. Food and Drug Administration (FDA) in 2023, providing an innovative treatment option for patients with dry eye disease.

Indications of Perfluorohexyl Octane Eye Drops (Miebo)

Targeted Treatment for Dry Eye Disease

Perfluorohexyl Octane Eye Drops are specifically used to treat the signs and symptoms of dry eye disease.

This drug has been verified through rigorous clinical trials and is mainly intended for patient populations with a history of dry eye disease and accompanying clinical symptoms of meibomian gland dysfunction.

Specifications and Properties of Perfluorohexyl Octane Eye Drops (Miebo)

Basic Physical Properties

Perfluorohexyl Octane Eye Drops are a sterile, clear and colorless ophthalmic solution, with the active ingredient content being 100% perfluorohexyl octane.

The chemical name of this semifluorinated alkane is 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane.

Molecular Structure Characteristics

The molecular formula of the active ingredient is C₁₄H₁₇F₁₃, and its molecular weight is 432.26 g/mol.

In terms of physicochemical properties, perfluorohexyl octane is almost immiscible with water, but it is miscible with ethanol and most organic solvents.

Packaging Specifications

Each multi-dose bottle contains 3 mL of perfluorohexyl octane, with a density of 1.338 g/mL, presenting as a clear and colorless liquid.

The drug is packaged in a 5 mL polypropylene bottle for multiple uses, equipped with a dropper tip and a screw cap.

Storage Methods of Perfluorohexyl Octane Eye Drops (Miebo)

Temperature Control Requirements

Perfluorohexyl Octane Eye Drops should be stored at a temperature of 15ºC to 25ºC (59ºF to 77ºF).

This storage temperature range ensures that the drug maintains stability and therapeutic efficacy throughout its shelf life.

Usage Period After Opening

After the drug bottle is opened, the drug can continue to be used within the expiration date marked on the bottle.

Proper Storage Practices

To ensure the quality of the drug, it should be stored away from extreme temperature environments, including freezing or exposure to high-temperature conditions.

At the same time, the bottle cap should be kept tightly closed to prevent contamination and evaporation.