Orlistat (Xenical) is a prescription medication for obesity management. It aids in weight control by inhibiting gastrointestinal lipases to reduce fat absorption.

Indications for Orlistat (Xenical)

Obesity Management

Applicable to patients with simple obesity who have an initial Body Mass Index (BMI) ≥ 30 kg/m², or patients with a BMI ≥ 27 kg/m² accompanied by risk factors such as hypertension, diabetes, and hyperlipidemia.

It must be used in combination with a low-calorie diet (daily fat intake not exceeding 30% of total calories) to achieve weight loss and weight maintenance.

Prevention of Weight Regain

For patients who have successfully lost weight in the past, Orlistat can reduce the risk of weight regain and requires long-term cooperation with dietary management.

Precautions

Before using the medication, organic causes of obesity (such as hypothyroidism) must be ruled out. It is not suitable for pregnant women, patients with chronic malabsorption syndrome, or patients with cholestasis.

Dosage Form, Strength and Properties of Orlistat (Xenical)

Dosage Form and Strength

Orlistat is available as 120 mg turquoise hard capsules. The capsule shell is printed with the black text "XENICAL 120".

Ingredients

Active Ingredient: Each capsule contains 120 mg of orlistat.

Excipients: Microcrystalline cellulose, sodium starch glycolate, sodium lauryl sulfate, povidone, talc, etc. The capsule shell contains gelatin, titanium dioxide, FD&C Blue No. 2, and black printing ink.

Pharmacological Action

Orlistat reversibly inhibits gastrointestinal lipases, blocking the breakdown of dietary fats (triglycerides) into absorbable free fatty acids, thereby reducing fat absorption by approximately 30%.

Storage Methods for Orlistat (Xenical)

Temperature Requirement

Store in an environment between 15°C and 30°C (59°F and 86°F), avoiding high temperatures or freezing.

Packaging and Expiration Date

Keep the original packaging bottle tightly closed to prevent moisture absorption.

Expired medications must not be used and should be discarded after the expiration date marked on the bottle.

Other Tips

Store it out of the reach of children to prevent accidental ingestion.

If there is any remaining medication to be discarded, it is recommended to handle it through professional drug recycling channels.

Do you need me to format this English translation into a printable PDF document for you, making it easier to store or share with medical professionals?