Binimetinib (Mektovi) is a targeted drug for the treatment of BRAF-V600E or V600K mutation-positive unresectable or metastatic melanoma. It inhibits the growth and spread of diseased cells by inhibiting MEK kinase, blocking the MAPK signaling pathway. Binimetinib is often used in combination with cannefenib to improve the efficacy of treatment.

Binimetinib(Mektovi) Uses, Usage

Binimetinib is primarily used for the treatment of BRAF-V600E or V600K mutation-positive unresectable or metastatic melanoma. It inhibits the proliferation and survival of diseased cells by inhibiting MEK kinases and blocking the MAPK signaling pathway. Binimetinib is often used in combination with canafenib to enhance the therapeutic effect.

Indications for Binimetinib

Binimetinib is indicated for the treatment of patients with metastatic or unresectable melanoma confirmed by an FDA-approved test with BRAF-V600E or V600K mutations. It prolongs the progression-free survival of patients by inhibiting MEK kinase, blocking the growth and spread of diseased cells.

Usage of Binimetinib

The recommended dose of Binimetinib is 45 mg orally twice daily, approximately 12 hours apart, in combination with canafenib until disease progression or unacceptable toxicity. Binimetinib can be taken with or without food. If the patient develops vomiting after taking Binimetinib, no additional dose is required, but the patient should continue to take the next dose as scheduled.

The use of Binimetinib needs to be adjusted according to the specific situation of the patient, especially in combination with canafenib. Next, we will cover the side effects of Binimetinib.

Binimetinib side effects

Common side effects of Binimetinib include nausea, diarrhea, fatigue, vomiting, and abdominal pain. Patients should regularly monitor these adverse effects during the medication period and take appropriate countermeasures according to the doctor's recommendations.

Common side effects

Common side effects of Binimetinib include nausea, diarrhea, fatigue, vomiting, and abdominal pain. For nausea and vomiting, people may try dividing meals or using antiemetic medications. Diarrhea and abdominal pain can be relieved by adjusting the dose or using painkillers. Fatigue is a common side effect of Binimetinib, and patients should ensure adequate rest and proper exercise.

Serious side effects

Binimetinib may cause serious side effects such as cardiomyopathy, venous thromboembolism, ocular toxicity, and hepatotoxicity. Patients should have regular cardiac function, visual acuity, and liver function tests during the medication. If you experience blurred vision, heart discomfort, or abnormal liver function, you should seek immediate medical attention and adjust your treatment plan according to your doctor's recommendations.

The side effects of Binimetinib need to be closely watched by patients and reviewed regularly, and below, we will introduce the price of Binimetinib.

How much is a box of Binimetinib?

The price of Binimetinib varies depending on the manufacturer and specifications. 

Binimetinib price and specifications

The price of Binimetinib is closely related to its specifications. Patients can choose the appropriate specifications according to their needs.

Price advantage over Binimetinib

The price of the Laos Lucius version is relatively low. This makes the Lao Lucius version of Binimetinib an economic option for many patients. Patients should pay attention to the authenticity and production date of the drug when purchasing, and avoid buying counterfeit or inferior drugs.

Binimetinib is a prescription drug, and patients should strictly follow the doctor's instructions when using it and have regular reexaminations to prevent possible serious adverse reactions.