BRAFTOVI(Encorafenib) Side Effects

Common side effects of TEMBEXA® include gastrointestinal issues, such as diarrhea, nausea, vomiting, and abdominal pain, affecting at least 2% of treated patients. 

Adverse Reactions to TEMBEXA®

Hepatic side effects such as increased liver enzymes (ALT, AST) and elevated bilirubin levels have also been observed, necessitating ongoing liver monitoring during treatment. There is also a risk of carcinogenicity, as TEMBEXA® is considered a potential human carcinogen based on animal studies. 

If gastrointestinal adverse events are severe, the second dose may be withheld. Additionally, patients should avoid concomitant use with intravenous cidofovir due to potential interactions.