Nitroxolin Capsules (Nitroxolinforte) is an antibacterial medication specifically indicated for the treatment of urinary tract infections. As a quinolone derivative, it possesses a unique dual mechanism of action with both antibacterial and antifungal properties, primarily targeting common pathogens associated with urinary tract infections.

What is Nitroxolin Capsules (Nitroxolinforte)?

Mechanism of Action and Therapeutic Characteristics

The medication inhibits the adhesion of bacteria to tissue cells, blocking the establishment of early-stage infections.

Simultaneously, it interferes with the metabolic activities of yeasts, effectively inhibiting fungal growth.

Its active ingredient is excreted via the kidneys, achieving effective therapeutic concentrations in urine to act directly on the site of infection.

Main Indications

Indicated for the treatment of acute and chronic urinary tract infections, including bacterial infections and yeast infections caused by nitroxolin-sensitive microorganisms.

Particularly suitable for the prophylactic treatment of recurrent urinary tract infections (relapse prevention).

Target Population

Specifically designed for adult patients; not recommended for children and adolescents under 18 years of age.

For elderly patients, individualized dosage adjustment is required based on renal function status.

Specifications and Dosage Form of Nitroxolin Capsules (Nitroxolinforte)

Dosage Form and Strengths

Nitroxolin Capsules are oral softgel formulations, with each capsule containing 250 mg of nitroxolin as the primary active ingredient.

Commercially available packaging options include 10-count, 20-count, 50-count, and 100-count configurations.

Physical Characteristics

The capsules are uniquely designed as dark red, oblong softgels.

This dosage form adopts advanced softgel technology to ensure the stability and bioavailability of the drug ingredients.

The capsule shell features excellent sealing properties, effectively protecting the internal drug components from environmental influences.

Excipient Composition

The capsules contain multiple pharmaceutical excipients, including yellow beeswax, hydrogenated soybean oil, partially hydrogenated soybean oil, soy lecithin, and medium-chain triglycerides, which collectively form a complete drug delivery system.

Storage Methods for Nitroxolin Capsules (Nitroxolinforte)

Temperature Control

Must be stored at a temperature not exceeding 25°C (77°F) to avoid the impact of high temperatures on drug stability.

The medication is temperature-sensitive, and compliance with storage temperature requirements is essential.

Protective Measures

Avoid direct sunlight and humid environments.

Maintain the integrity of the original packaging.

Store in a secure location out of the reach of children.

Protect from heat and avoid proximity to heat sources.

Expiry Date Management

Use strictly in accordance with the expiry date indicated on the packaging; the expiration date refers to the last day of the specified month.

Expired medications should be properly disposed of promptly and must not be used.