Vadadustat(Vafseo)
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Manufacturer:
Akebia Therapeutics
Validity period:
36 months
Reminder: The outer packaging is for reference only, please purchase and use under the guidance of
a
pharmacist. For read by medical and pharmaceutical professionals only.
Vafseo(Vadadustat) Instructions:Uses,Dosage, Side Effects
VAFSEO, with the generic name vadadustat, is an orally administered hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor. It received initial U.S. approval in 2024. The medication is formulated as film-coated, immediate-release tablets designed for once-daily oral administration. Its primary pharmacological action involves stabilizing hypoxia-inducible factors to stimulate endogenous erythropoietin production, thereby supporting red blood cell formation in eligible patient populations.
Generic name
Vadadustat(Vafseo)
Indications
VAFSEO is indicated specifically for the treatment of anemia due to chronic kidney disease in adult patients receiving dialysis for a minimum of three months.
Therapeutic Target
HIF Prolyl Hydroxylase (HIF-PH) Isoforms 1, 2, and 3.
Active Ingredients
Vadadustat (2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid).
specifications
300mg * 60 Tablets/Bottle
Dosage and Administration
The recommended starting dose is 300 mg taken orally once daily, with or without food.
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